In general, if you are using a compiled PMDF configuration then you will need to recompile it after any changes to the files that comprise the PMDF compiled configuration: the PMDF configuration file and any files it includes, the alias file and any files it includes (but not alias database or mailing list files), the option file and any files it includes, the mappings file and any files it includes, the conversions file and any files it includes, the system wide filter file, the circuit check configuration file, and the security configuration file and any files it includes.

In general, you will need to restart any resident processes after any changes of which that resident process needs to be aware; such changes may include changes to the basic PMDF configuration (such as the changes above requiring recompilation of a compiled configuration) and may also include other, component-specific changes.